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21238 Highway 49 , Saucier, MS 39574

$350,000

2 full · 1 half
baths
2,500
sqft
2008
year built

Commercial Property for Sale or Lease on Hwy 49! Prime Commercial Opportunity with Exceptional Visibility Located directly on Highway 49, this well-maintained brick commercial building offers outstanding exposure, boasting approximately 2,500 square feet of flexible space on a generous 1.3-acre lot. The property features an impressive 183 feet of highway frontage, ensuring maximum visibility to the 15,000 vehicles that pass daily, as reported by MDOT. Property Features • Total Building Size: Approximately 2,500 sq. ft. • Lot Size: 1.3 acres • Highway Frontage: 183 feet along Hwy 49 • Traffic Count: 15,000 vehicles per day Building Details The rear entrance opens to an 800± square foot space, previously utilized as a medical cannabis dispensary. This area is fully equipped, with all fixtures, furnishings, and equipment remaining on-site. Included are a comprehensive security monitoring system, a secure vault, and display cabinets, making it ideal for a variety of business uses. In addition to the dispensary space, there are approximately 1,700 square feet available, offering significant additional income potential for new owners or lessees. Versatile Layout and Potential Uses The property was previously home to The Relief Clinic and was originally constructed as a model home. With a zoning change, the building could be converted back to residential use, providing further flexibility. Suite A within the building is designed for comfort and functionality, featuring a kitchen, two bedrooms, two bathrooms, and a spacious living area complete with a fireplace.

Highlights

  • Commercial Sale
  • Mixed Use
  • Built in 2008
  • 1.3 Acre Lot
  • 296 days on Market

  • Bathrooms
    2 full · 1 half
  • Year Built
    2008
  • Stories
    1.0

  • Acres
    1.3

  • County
    Harrison
  • City
    Saucier
  • Zip Code
    39574

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Frequently Asked Questions

How do I schedule a tour of 21238 Highway 49?

We can make that happen quickly. Click Tour This Home and we'll connect you directly with our vetted local partner to schedule your visit to 21238 Highway 49.

They know commercial sales in the area well and can give you the guidance you need to buy with confidence.

How do I get more information about 21238 Highway 49?

Click Ask a Question to talk with our team. You already know it is a N/A bed, 2 bath, listed for $350,000. We can talk through recent upgrades, potential seller motivation, how this mixed use compares to others in Saucier, and can even get you in to see the property quickly.

How much is the monthly mortgage payment for 21238 Highway 49?

With a 20% down payment and a 30-year fixed loan at an illustrative 7.25% rate, the ez Mortgage Calculator estimates the monthly payment for 21238 Highway 49 at around $2,203. This includes estimated property taxes and insurance.

Want to see how this changes with different down payments or interest rates? Jump to the calculator to run the numbers and fine-tune your plan.

How do I get pre-approved to buy 21238 Highway 49?

Stand out in a competitive market by getting pre-approved today. Our quick and private pre-approval process helps you understand your true buying power—no credit pull required to explore all of your options.

Or, let us connect you with our preferred local lender in Harrison County. They will give you all of your available financing options, based on your specific situation and what is available to you.

Can I negotiate the asking price for 21238 Highway 49?

In most cases, yes. Whether 21238 Highway 49 is priced competitively or not, your best offer depends on your personal situation, the seller's timeline, and recent activity in Saucier's market. Our preferred local partner will help you craft a strategy—factoring in comparable properties that have sold, timing, and deal structure—to make a smart, strong offer. Click here to ask about negotiation opportunities.

How do I make an offer on 21238 Highway 49?

We can handle that for you. Our preferred local agent specializes in commercial sales in Saucier and can guide you through every step of the offer process.

You need an expert who is looking out for your best interests. From market valuation to contingencies and timing, they'll help you present a compelling offer that fits your goals. Click Ask a Question to get started today.

What is the price per square foot for this home?

This home is listed at $350,000 with 2,500 sqft of space—that comes out to approximately $140 per square foot.

How long has this property been on the market?

21238 Highway 49 was listed on January 19, 2026, which means it's been on the market for 296 days.

Want to keep tabs on it? Click the ♥ to favorite this home and get notified of price drops or changes.

When was this house built?

This home was built in 2008, making it approximately 18 years old.

What is the lot size of this property?

21238 Highway 49 sits on a 1.3-acre lot, which is 56,628 square feet.

What are the property taxes for 21238 Highway 49?

The most recent public record shows annual property taxes for 21238 Highway 49 were approximately $2,531. This may change with reassessment or exemptions. Our local partner can verify current tax amounts and help you estimate future costs based on your situation.

Is 21238 Highway 49 still available for sale?

Yes, this home is still available! Click the ♥ to favorite it so you don't miss any changes—or ask our local expert to schedule a time to see it in person.

Source: ez Home Search, MLS Data

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Listing information provided exclusively for consumers' personal, non-commercial use and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. Information deemed reliable but not guaranteed by the MLS. The listing broker’s offer of compensation is made only to participants of the MLS where the listing is filed. Copyright 2026, MLS United. All rights reserved.

Last Updated: November 11, 2026 at 07:35PM | Source: MLS United | MLS#: 4136622