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The historical significance of this mostly renovated building, combined with the prime downtown location on the Gainesville Square across the street from the Ozark County Courthouse, makes it a rare opportunity indeed. The fact that the upper units were once hotel rooms adds to its charm and potential.The current state of the property is quite impressive, as it has undergone extensive renovations. The lower level, previously operating as a doctor's office, has been tastefully restored while retaining its original wood floors and architectural features. The modern upgrades, i.e., new pex pipe plumbing, updated electrical systems, crown molding, insulation, central air, plus Marble floors in BA & counters in reception area, new cabinetry and fresh paint, ensure that it offers all the comforts of contemporary living. The flexible layout allows for various professional uses, including medical practices, retail stores, insurance agencies, private schools, and more.While the lower level is move-in ready, the upper level presents an opportunity for someone with a creative vision. Although it requires TLC, it already boasts new windows and evidence of initial improvements. Overall, this property offers a unique blend of history, modern updates, and unlimited possibilities. Whether you're a seasoned investor or someone looking for a distinctive business location, this listing is sure to capture your interest. Don't miss this chance to own a piece of history in downtown Gainesville.

Highlights

  • Commercial Sale
  • Office
  • Built in 1940
  • 0.06 Acre Lot
  • 293 days on Market

  • Bathrooms
    2
  • Year Built
    1940
  • Parking Features
    On Street
  • Security Features
    Smoke Detector(s), Security System
  • Cooling
    Ceiling Fan(s), Central Air
  • Heating
    Wall Furnace, Propane

  • Acres
    0.06
  • View
    City
  • Utilities
    Sewer Available, Electricity Available, Water Available, Natural Gas Available

  • County
    Ozark
  • City
    Gainesville
  • Neighborhood
    N/A
  • Zip Code
    65655

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Frequently Asked Questions

How do I schedule a tour of 333 Main St?

We can make that happen quickly. Click Tour This Home and we'll connect you directly with our vetted local partner to schedule your visit to 333 Main St.

They know commercial sales in the area well and can give you the guidance you need to buy with confidence.

How do I get more information about 333 Main St?

Click Ask a Question to talk with our team. You already know it is a N/A bed, 2 bath, listed for $140,000. We can talk through recent upgrades, potential seller motivation, how this office compares to others in Gainesville, and can even get you in to see the property quickly.

How much is the monthly mortgage payment for 333 Main St?

With a 20% down payment and a 30-year fixed loan at an illustrative 7.25% rate, the ez Mortgage Calculator estimates the monthly payment for 333 Main St at around $902. This includes estimated property taxes and insurance.

Want to see how this changes with different down payments or interest rates? Jump to the calculator to run the numbers and fine-tune your plan.

How do I get pre-approved to buy 333 Main St?

Stand out in a competitive market by getting pre-approved today. Our quick and private pre-approval process helps you understand your true buying power—no credit pull required to explore all of your options.

Or, let us connect you with our preferred local lender in Ozark County. They will give you all of your available financing options, based on your specific situation and what is available to you.

Can I negotiate the asking price for 333 Main St?

In most cases, yes. Whether 333 Main St is priced competitively or not, your best offer depends on your personal situation, the seller's timeline, and recent activity in Gainesville's market. Our preferred local partner will help you craft a strategy—factoring in comparable properties that have sold, timing, and deal structure—to make a smart, strong offer. Click here to ask about negotiation opportunities.

How do I make an offer on 333 Main St?

We can handle that for you. Our preferred local agent specializes in commercial sales in Gainesville and can guide you through every step of the offer process.

You need an expert who is looking out for your best interests. From market valuation to contingencies and timing, they'll help you present a compelling offer that fits your goals. Click Ask a Question to get started today.

What is the price per square foot for this home?

This home is listed at $140,000 with 2,015 sqft of space—that comes out to approximately $69 per square foot.

How long has this property been on the market?

333 Main St was listed on January 23, 2026, which means it's been on the market for 293 days.

Want to keep tabs on it? Click the ♥ to favorite this home and get notified of price drops or changes.

When was this house built?

This home was built in 1940, making it approximately 86 years old.

What is the lot size of this property?

333 Main St sits on a 0.06-acre lot, which is 2,614 square feet.

What are the property taxes for 333 Main St?

The most recent public record shows annual property taxes for 333 Main St were approximately $1,263. This may change with reassessment or exemptions. Our local partner can verify current tax amounts and help you estimate future costs based on your situation.

Is 333 Main St still available for sale?

Yes, this home is still available! Click the ♥ to favorite it so you don't miss any changes—or ask our local expert to schedule a time to see it in person.

Source: ez Home Search, MLS Data

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The data relating to real estate for sale on this web page comes in part from the Internet Data Exchange (IDX) of Southern Missouri Regional MLS. Real estate listings held by Brokerage firms other than ReeceNichols Real Estate are marked with the IDX logo and detailed information about them includes the name of the listing Brokers. The information being provided is for consumers' personal, noncommercial use and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. The information being provided is deemed reliable but not guaranteed, and all information should be verified by the consumer. Any representation that a website contains all listings shall only mean that the website contain all listing available to the public through the IDX data feed. There may be other properties offered through a REALTOR® that have not been displayed on this site. Information deemed reliable but not guaranteed. Copyright © 2026 Southern Missouri Regional MLS. All Rights Reserved.