Searching ...

Iconic site with a long and rich history for sale in downtown Dubuque. Lot One has been improved with $2.1 million in infrastructure including new sewer, electric, water, gas systems, and first floor bar with beautifully crafted woodwork by Smith Home Gallery & Cabinet Works (2002). In 2006 the sellers added a full commercial kitchen and in 2012 a custom-built bar on the second floor. This five-story cornerstone currently boasts a bar/restaurant area on the first floor, the second floor offers an area for private parties with a private bar and commercial kitchen, floors three, four, and five are ready for development. The sellers have blueprint plans for apartments available by request. Imagine the possibilities on the rooftop with its sweeping views of the Mississippi River and downtown! Nestled in the vibrant cultural and business hub of Dubuque, Lot One is in extremely close proximity to specialty shops, dining, live music, entertainment, art, gift shops, and more. This is where Dubuque started. This remarkable site was the first lot established in Dubuque in 1835, predating Iowa’s statehood! A full outline of Lot One’s abundant history is located in the documents section. Whether you're looking to expand your hospitality portfolio, launch a signature venue, or develop luxury condos or residential units, Lot One offers unmatched potential wrapped in over 190 years of Dubuque heritage. Video Tour: https://vimeo.com/1080046511

Highlights

  • Commercial Sale
  • Industrial
  • Built in 1919
  • 190 days on Market

  • Year Built
    1919
  • Stories
    5.0
  • Construction Materials
    Brick
  • Foundation
    Concrete Perimeter
  • Flooring
    Concrete, Wood
  • Cooling
    Central Air
  • Heating
    Forced Air, Natural Gas
  • Basement
    Full

  • Utilities
    Natural Gas Available
  • Water
    Public


Ask a Question

What's your home worth?

Calculate your current home value within seconds.

Frequently Asked Questions

How do I schedule a tour of 100 Main St?

We can make that happen quickly. Click Tour This Home and we'll connect you directly with our vetted local partner to schedule your visit to 100 Main St.

They know commercial sales in the area well and can give you the guidance you need to buy with confidence.

How do I get more information about 100 Main St?

Click Ask a Question to talk with our team. You already know it is a N/A bed, N/A bath, listed for $990,000. We can talk through recent upgrades, potential seller motivation, how this industrial compares to others in Dubuque, and can even get you in to see the property quickly.

How much is the monthly mortgage payment for 100 Main St?

With a 20% down payment and a 30-year fixed loan at an illustrative 7.25% rate, the ez Mortgage Calculator estimates the monthly payment for 100 Main St at around $5,634. This includes estimated property taxes and insurance.

Want to see how this changes with different down payments or interest rates? Jump to the calculator to run the numbers and fine-tune your plan.

How do I get pre-approved to buy 100 Main St?

Stand out in a competitive market by getting pre-approved today. Our quick and private pre-approval process helps you understand your true buying power—no credit pull required to explore all of your options.

Or, let us connect you with our preferred local lender in Dubuque County. They will give you all of your available financing options, based on your specific situation and what is available to you.

Can I negotiate the asking price for 100 Main St?

In most cases, yes. Whether 100 Main St is priced competitively or not, your best offer depends on your personal situation, the seller's timeline, and recent activity in Dubuque's market. Our preferred local partner will help you craft a strategy—factoring in comparable properties that have sold, timing, and deal structure—to make a smart, strong offer. Click here to ask about negotiation opportunities.

How do I make an offer on 100 Main St?

We can handle that for you. Our preferred local agent specializes in commercial sales in Dubuque and can guide you through every step of the offer process.

You need an expert who is looking out for your best interests. From market valuation to contingencies and timing, they'll help you present a compelling offer that fits your goals. Click Ask a Question to get started today.

What is the price per square foot for this home?

This home is listed at $990,000 with 12,540 sqft of space—that comes out to approximately $79 per square foot.

How long has this property been on the market?

100 Main St was listed on May 04, 2026, which means it's been on the market for 190 days.

Want to keep tabs on it? Click the ♥ to favorite this home and get notified of price drops or changes.

When was this house built?

This home was built in 1919, making it approximately 107 years old.

Is 100 Main St still available for sale?

Yes, this home is still available! Click the ♥ to favorite it so you don't miss any changes—or ask our local expert to schedule a time to see it in person.

Source: ez Home Search, MLS Data

Popular Home Searches in Dubuque, IA


Search Nearby Cities


Search Nearby Postal Codes

The data relating to real estate for sale on this website comes in part from the Internet Data exchange (IDX) program of Dubuque Multiple Listing Service. IDX information is provided exclusively for consumers' personal, non-commercial use and may not be used for any purpose other than to identify prospective properties consumers may be interested in purchasing. Information deemed reliable but not guaranteed. Copyright 2026 Dubuque Multiple Listing Service. All Rights Reserved.

Last Updated: November 10, 2026 at 09:44AM | Source: East Central Iowa Association of REALTORS | MLS#: 154540