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PHENOMENAL INVESTMENT | SECURED 13-YEAR FEDERAL GOVERNMENT TENANT | TRIPLE NET | BUILT IN 2019 | SOUTH SF BIOTECH HUB! A rare investment opportunity in the heart of South San Francisco's world-renowned biotech and life sciences hub! Purpose-built in 2019, this premier 21,552 SF high-tech facility sits on an expansive 3.65-acre site and offers the stability of a secured 13-year federal government tenant under a Triple Net lease, combined with sophisticated, mission-critical infrastructure. The facility features approximately 9,500 SF of professional office space, 4,500 SF of specialized laboratory space, and a 7,000 SF warehouse and inspection area. The technical build-out includes multiple entomology and botany labs, 100% ducted exhaust, high-purity reverse osmosis water systems, a 500kW stand-alone diesel generator, and dedicated UPS backup power. Designed for secure government operations, the property features a Lenel card-access system, 24-hour CCTV, blast-mitigation windows, secured fencing, four interior dock-high doors accommodating 53-foot tractor-trailers, and 62 assigned parking spaces. Strategically positioned within the South San Francisco Life Science cluster. Don't miss this phenomenal opportunity!

Highlights

  • Commercial Sale
  • Industrial
  • Built in 2019
  • 3.65 Acre Lot
  • 203 days on Market

  • Year Built
    2019
  • Parking Features
    Assigned
  • Living Area
    21552.0
  • Flooring
    Concrete, Other
  • Heating
    Forced Air

  • Acres
    3.65
  • Water
    Public

  • County
    San Mateo
  • City
    South San Francisco
  • Zip Code
    94080

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Frequently Asked Questions

How do I schedule a tour of 560 Eccles Ave?

We can make that happen quickly. Click Tour This Home and we'll connect you directly with our vetted local partner to schedule your visit to 560 Eccles Ave.

They know commercial sales in the area well and can give you the guidance you need to buy with confidence.

How do I get more information about 560 Eccles Ave?

Click Ask a Question to talk with our team. You already know it is a N/A bed, N/A bath, listed for $41,000,000. We can talk through recent upgrades, potential seller motivation, how this industrial compares to others in South San Francisco, and can even get you in to see the property quickly.

How do I get a virtual tour of 560 Eccles Ave?

Yes! A virtual tour is available for 560 Eccles Ave. Click here to view the full walkthrough and explore every room at your own pace. If you would like a guided virtual showing or have questions along the way, we can connect you with our local expert to walk you through it live.

How much is the monthly mortgage payment for 560 Eccles Ave?

With a 20% down payment and a 30-year fixed loan at an illustrative 7.25% rate, the ez Mortgage Calculator estimates the monthly payment for 560 Eccles Ave at around $233,320. This includes estimated property taxes and insurance.

Want to see how this changes with different down payments or interest rates? Jump to the calculator to run the numbers and fine-tune your plan.

How do I get pre-approved to buy 560 Eccles Ave?

Stand out in a competitive market by getting pre-approved today. Our quick and private pre-approval process helps you understand your true buying power—no credit pull required to explore all of your options.

Or, let us connect you with our preferred local lender in San Mateo County. They will give you all of your available financing options, based on your specific situation and what is available to you.

Can I negotiate the asking price for 560 Eccles Ave?

In most cases, yes. Whether 560 Eccles Ave is priced competitively or not, your best offer depends on your personal situation, the seller's timeline, and recent activity in South San Francisco's market. Our preferred local partner will help you craft a strategy—factoring in comparable properties that have sold, timing, and deal structure—to make a smart, strong offer. Click here to ask about negotiation opportunities.

How do I make an offer on 560 Eccles Ave?

We can handle that for you. Our preferred local agent specializes in commercial sales in South San Francisco and can guide you through every step of the offer process.

You need an expert who is looking out for your best interests. From market valuation to contingencies and timing, they'll help you present a compelling offer that fits your goals. Click Ask a Question to get started today.

What is the price per square foot for this home?

This home is listed at $41,000,000 with 21,552 sqft of space—that comes out to approximately $1,902 per square foot.

How long has this property been on the market?

560 Eccles Ave was listed on April 23, 2026, which means it's been on the market for 203 days.

Want to keep tabs on it? Click the ♥ to favorite this home and get notified of price drops or changes.

When was this house built?

This home was built in 2019, making it approximately 7 years old.

What is the lot size of this property?

560 Eccles Ave sits on a 3.65-acre lot, which is 158,994 square feet.

Is 560 Eccles Ave still available for sale?

Yes, this home is still available! Click the ♥ to favorite it so you don't miss any changes—or ask our local expert to schedule a time to see it in person.

Source: ez Home Search, MLS Data

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